What are the symptoms of chronic renal failure?

What are the symptoms of chronic renal failure? The symptoms of specific knowledge, is the basis of patient choice of treatment, the patients of course, a comprehensive understanding of the patient's symptoms are different, patients in the choice of treatment will vary, chronic renal failure The symptoms and signs are described in detail here, patients can fully understand.
Symptoms of chronic renal failure 1) hyponatremia and hypernatremia: symptoms of chronic renal failure due to vomiting, diarrhea, sodium lost too many symptoms of chronic renal failure, renal tubular reabsorption of sodium to reduce the symptoms of chronic renal failure-prone hyponatremia, manifested as fatigue, anorexia, serious cases of hypotension and even coma. Such as a sudden increase in sodium intake, the symptoms of chronic renal failure prone water, sodium retention, hypertension, edema and heart failure.
Symptoms of chronic renal failure, 2) high potassium and hypokalemia: renal failure, oliguria potassium excretion decreased. Increased catabolism of the body, metabolic acidosis, potassium is transferred to the extracellular, the symptoms of chronic renal failure, retention of potassium-sparing diuretics or Angiotensin converting enzyme inhibitors, symptoms of chronic renal failure can lead to serious hyperkalemia. Manifested as drowsiness, severe arrhythmias and even cardiac arrest. Eating fewer symptoms of chronic renal failure, inadequate potassium intake, nausea, vomiting, diarrhea and long-term application of row potassium diuretics. Prone to hypokalemia. Chronic renal failure symptoms as fatigue, muscle weakness, abdominal distention, paralysis of limbs and severe cases, serious arrhythmias and respiratory muscle paralysis.
Introduced is more than the symptoms of chronic renal failure, the patient can carry out a comprehensive understanding of the patient in the choice of treatment method, you need to communicate with their physicians, and in the process of treatment, patients should always reflect the changes in their own illness, to change the treatment program at any time, and in the time of treatment, but also always engaged in care work, and play a good role in promoting the effects of treatment, for the treatment of chronic renal failure in early to avoid evolved uremia, only depend on the method of dialysis treatment. Experts advise patients, the symptoms of chronic renal failure is the basis of the patients choice of treatment, the patients to fully understand.
What are the symptoms of chronic renal failure? Renal failure therapy users love tips! The third stage renal failure is kidney damage, renal failure, creatinine increased damage kidneys original renal function, resulting in the accumulation of a large number of toxins from the body, have a serious impact on the body. Early treatment is critical to reduce creatinine.

Symptoms of Chronic renal failure

Chronic renal failure can cause symptoms? Kind of problem a lot of kidney patients are asking, that is the term of the renal failure is to talk about from this point of view of the clinical manifestations. Thus the doctor not only to the time of diagnosis combined with the value of blood urea nitrogen, serum creatinine measured, more importantly, according to the symptoms of poisoning patients in the body's own judgment, not just underground diagnosis of renal failure should not increase the burden on the patient's thinking . Renal failure caused by symptoms, the site for you the following introduction:


Chronic renal failure can cause the symptoms? What is chronic renal failure? Chronic renal failure (CRF) is not an independent disease, but because of the deterioration of kidney damage caused by a variety of reasons progress to end-stage performance. Our common cause of glomerulonephritis, diabetic nephropathy, hypertensive nephropathy, polycystic kidney disease, obstructive kidney disease, and sometimes acute renal failure if not treated properly can also cause chronic renal failure. Shijiazhuang kidney disease hospital experts detail the symptoms of chronic renal failure.


The symptoms of chronic renal failure in a certain stage, early often have anorexia, nausea, vomiting, headache, fatigue and nocturnal enuresis. The gradual emergence of oliguria, edema or high blood pressure most of the patients mouth odor, oral mucosal ulcers, epistaxis or gastrointestinal bleeding, can be difficult to focus attention, unresponsive, limb numbness, drowsiness or restlessness, and other neuropsychiatric symptoms. Chronic renal failure caused by various system-related symptoms.


Chronic renal failure can cause the following symptoms:


1, the gastrointestinal tract: the earliest and most common symptoms


Anorexia (loss of appetite earliest), nausea, vomiting, abdominal distension, tongue, mouth ulcers, oral ammonia odor, such as gastrointestinal bleeding;


2, the blood system:


a. anemia: must have symptoms of uremic patients, mainly due to renal secretion stimulate erythropoietin reduced the inhibition of red blood cells and blood generated;


b. bleeding tendencies: can be expressed as the skin, mucous membrane bleeding, and increased destruction of platelets, prolonged bleeding time and so on, may be caused by toxins, dialysis can be quickly corrected;


abnormal white blood cells: Reduce, chemotaxis, phagocytosis and bactericidal diminished capacity, and prone to infection, dialysis can improve;


3, the cardiovascular system: renal failure, the most common cause of death, including hypertension, heart failure, pericarditis, arterial atherosclerosis, etc.;


4, nerve, muscle system performance:


a. early: fatigue, insomnia, inability to concentrate, personality change, neuromuscular excitability increase, such as muscle trembling, hiccups, mental disorders: delirium, convulsions, hallucinations, and coma;


B. Late: peripheral neuropathy, sensory nerves than motor nerves significantly, paresthesia: acral sock-like distribution of sensory loss, muscle weakness: proximal muscle involvement is more common;


c dialysis disequilibrium syndrome: blood urea nitrogen to reduce the excessive intracellular and extracellular osmotic imbalance, caused by increased intracranial pressure and cerebral edema due performance of nausea, vomiting, headache, severe cases, convulsions;


5, renal osteodystrophy: is the general term for the bone changes uremia


can cause spontaneous fractures;


b. and uncommon symptoms, such as bone pain, difficulties in walking;


6, the respiratory system performance:


a. acidosis, breathing deep and long;


b uremia bronchitis, pneumonia (butterfly wings), pleurisy, etc.;


Skin symptoms: pruritus, urea frost deposition, uremic face


8, endocrine disorders:


a hormone generated by renal decline;


b hormone degradation in the kidney can be increased;


9 Ease of severe infection: fever, infection, not normal obviously


10, metabolic disorders, and others:


a. hypothermia: the temperature is lower than normal people about 1oC (estimated fever should be considered), basal metabolic rate is often decreased;


b. abnormal glucose metabolism: normal patients: impaired glucose tolerance, patients with diabetes: the insulin dosage should be reduced (to reduce degradation);


c lipid metabolism abnormalities: TC normal, TG and LDL and of VLDL increased, HDL decreased, dialysis can not be corrected, chronic dialysis patients with premature atherosclerosis;


d hyperuricemia: GFR <20, of uric acid clearance impairment, gouty arthritis is rare;

Had renal failure, urine output will change?

Had renal failure, urine output will change? ? Patients concerned about the kind of problem is very correct, early chronic renal failure can be improved it? Decompensated renal function should be actively treating the primary disease protection and prevention of kidney from other external factors damage, such as avoiding the use of drugs with renal toxicity; renal insufficiency in decompensated should prevent or remove exacerbate factors. Alleviate symptoms and prevent renal deterioration; the treatment of chronic renal failure should be limited to protein intake, correction of water, electrolyte and acid-base balance disorder. The following is a Xiaobian finishing.
Early in chronic renal failure (CRF), about 2/3 of the disease increased urine output, glomerular filtration rate (GFR) decreased to 40ml/min appear polyuria or nocturia, GFR <30ml/min almost all disease there is more urine. 24 hours urine output is mostly in the 1500 ~ 2500ml, rarely more than 3500ml. The urine was light, due to the dysfunction concentration, urine specific gravity more than 1.016 or less. Clinically because of polyuria, El thirsty, and they tend to drink, and change of urine flow law of the day and night, nocturnal enuresis during the day, which is the earliest symptoms of CRF.
Polyuria must be accompanied by thirst, such as to allow patients free access to water, the thirst to regulate water metabolism can usually achieve a reasonable balance. Thirst is sometimes very serious, dry lips, the performance of the CRF late, may be caused by acidosis, hyperventilation and reduce the secretion of saliva. Subsequently decreased urine output with kidney dysfunction, when GFR fell to 50 ~ lOml / min or less, the urine in the following 1000ml. 24 hours urine output <400ml often prompts for the serious late manifestations. Continue to develop the disease, excessive destruction of renal units, the glomerular small number of renal blood flow disorder, unable to maintain the tube, oliguria. Such as the sudden appearance of oliguria (<400ml/24 hours) you should carefully check the existence of urinary tract obstruction and other complications such as heart failure.
For had renal failure urine will change? Renal failure therapy users love tips! Clinical manifestations of the clinical manifestations of chronic renal failure is caused by the retention of a variety of toxins and metabolites stay involving various systems of the body, chronic renal failure, an early manifestation of weakness, the spirit of the poor, poor appetite, nausea, vomiting and other digestive symptoms later. Condition of chronic renal failure in the further development of anemia, heart palpitations, skin itching, limb paresthesia, numbness. Late invasion and the cardiovascular system in chronic renal failure to hypertension, pericarditis, cardiomyopathy, cardiac arrhythmias and heart failure; invading the blood system, severe anemia, hemoglobin low 3g/dL, bleeding tendency (nose Nv, bleeding gums , skin ecchymosis, etc.); invasion and respiratory interstitial pneumonia, chronic renal failure X-rays show the hilar both sides of the butterfly-shaped shadow the bottom moist rales in the lungs, chronic renal failure patients with chest pain, and chest plot fluid performance.

The late symptoms of kidney failure

What are the late symptoms of kidney failure? Know how knowledge is very important, and renal failure can not easily be found, patients find themselves suffering from renal failure in a casual examination, but has come to late, that late renal failure symptoms what is it? We know that renal failure patients in advanced stage, will be severely affected by the patient, and only the timely detection of disease, proper treatment and prevention in order to better away from renal failure in patients with injury. The late symptoms of kidney failure are mainly the following points:


1, in patients with dehydration or edema, the concentrated urine of renal failure patients with renal function was reduced, resulting in polyuria, nocturia, combined with patients with anorexia, nausea, vomiting and diarrhea, Guchang exacerbated due to dehydration; the other hand, kidney drainage poor, drinking water will lead to water retention in the body, resulting in edema. Therefore, proper water supply has become an important measure of kidney failure.


2, anemia, kidney failure patients must have symptoms, kidney patients erythropoietin reduce the retention of the metabolites to inhibit the generation of red blood cells and damage the red cell membrane, it shortened life expectancy, the toxic substances present in the blood inhibit the activity of erythropoietin renal failure in patients with anorexia, diarrhea, bleeding easily lead to iron deficiency, folate deficiency and protein deficiency, in addition to the loss of protein in the urine is caused by an important cause of anemia.


3, the performance of the gastrointestinal tract, renal failure the earliest and most common symptoms. Anorexia, abdominal discomfort in the early and later nausea, vomiting, diarrhea, mouth smell of urine and oral mucosal ulceration, and even heavy bleeding and other symptoms associated with the digestive tract. Reason to cause gastrointestinal symptoms, the in vivo retention of toxic substances to cause some damage to the nervous system, coupled with the increase in the amount of urea excreted from the digestive tract, the role of bacteria or intestinal hydrolase to produce ammonium carbonate and ammonia, to stimulate the gastrointestinal mucous membranes, causing gastrointestinal dysfunction and varying degrees of mucosal inflammation and ulcers. In addition, water, electrolyte and acid-base balance is caused by a cause of gastrointestinal symptoms.


4, listlessness, fatigue, dizziness, headache, memory loss, insomnia, accompanied by limb numbness, hand, foot and burning, itching, to be constantly on the move, not repose. The late emergence of the symptoms of lethargy, irritability, delirium, muscle trembling, twitching, convulsions, and coma. Caused by mental, neurological symptoms of the reason is that the metabolite retention, water, electrolyte imbalance, metabolic acidosis, and hypertension result of factors working together.


5, patients with renal failure the body's immune function decreased resistance to infection is poor, very easily lead to secondary infection, a common lung and urinary tract infections, and infections occur often without significant systemic reactions, special attention should be signs of lung and urine change.


These are the advanced symptoms of renal failure is what introduced by understanding I believe you have a certain understanding of symptoms, early detection, early treatment and regular kidney hospital for treatment, will make the patient's best improved, although renal failure is the kind of hard to be found in disease, However, any kind of disease, as long as the disease, it has the root causes, as long as we carefully observe it, it will be harvested. If you have any questions, you can consult with our experts online.
Late symptoms for kidney failure is it? Renal failure Tips! Diet should be light, avoid spicy spicy food with chronic renal failure, uremic patients gastrointestinal mucosa often has congestion, erosion status, pepper, white wine, such as eating spicy food, often add to the erosion of the gastrointestinal mucosa, causing the blood vessels of the stomach lining bleeding.

The clinical manifestations of chronic renal failure

Chronic renal failure is the deterioration of various nephrotic disease development of end-stage nephropathy compensatory ability is very strong when only minor damage to the patients themselves did not have any symptoms, when the following chronic renal failure symptoms, suggesting that the disease has developed deterioration of the need to timely pay close attention to the treatment, or developed into uremia end-stage, the only long-term dialysis or kidney transplant to maintain life.
Since the kidney is one of the most important organ of the human body, bear the burden of the body excrete waste, once the kidney damage, kidney failure will hurt the various organs of the body, and a variety of complications. The following lists the part of the clinical symptoms of chronic renal failure:
A. Chronic renal failure caused by the performance of the water, electrolyte and acid-base balance disorders
(1) excessive water loss or water: normal renal water metabolism wider range of adjustment. Renal failure due to poor concentration function, nocturia, polyuria, coupled with loss of appetite, vomiting, diarrhea, and could easily cause dehydration due to poor kidney drainage, drinking water or rehydration improper prone to water retention, manifested as edema, hypertension , heart failure, and even pulmonary edema, cerebral edema and other serious consequences.
(2) hyponatremia and hypernatremia: vomiting, diarrhea, excessive sodium loss, tubular sodium reabsorption decreased, prone to hyponatremia, as fatigue, anorexia. Severe cases, hypotension and even coma. Such as a sudden increase in sodium intake, prone to water and sodium retention, hypertension, edema and heart failure.
(3) high potassium and hypokalemia: renal failure, oliguria potassium excretion reduced. Increase in catabolism of the body, metabolic acidosis, K + transferred to the extracellular retention of potassium-sparing diuretics or angiotensin-converting enzyme inhibitors, can lead to serious hyperkalemia. Manifested as drowsiness, severe arrhythmias and even cardiac arrest. If eating less potassium intake, and nausea. Vomiting, diarrhea, and long-term application of row potassium diuretics. Prone to hypokalemia. As fatigue, muscle weakness, abdominal distention, paralysis of limbs. In severe cases, serious arrhythmias and respiratory muscle paralysis.
(4) low calcium and high phosphorus: renal failure, the kidney can not generate active vitamin D3, calcium absorption from the gut to reduce, to the occurrence of hypocalcemia. Seldom symptoms. Only in the correction of acidosis with sodium bicarbonate may reduce free calcium and precipitate tetany. Renal units to reduce phosphorus excretion and hyperphosphatemia. Hyperphosphatemia enables the blood calcium and phosphorus product increased. Hypocalcemia increase in PTH secretion, and prone to renal osteodystrophy and metastatic calcification.
(5) hypermagnesemia: renal failure due to renal row of magnesium to reduce intestinal absorption of magnesium is still normal. Can lead to hypermagnesemia. As fatigue, skin flushing, burning, etc. Severe hypermagnesemia may occur severe symptoms such as respiratory and cardiac paralysis.
(6), metabolic acidosis: chronic renal failure due to the following reasons caused by metabolic acidosis;
① renal failure metabolites, such as phosphoric acid, sulfuric acid and acetoacetate acid retention due to renal excretion of obstacles;
② renal tubular secretion of hydrogen ions in the functional impairment caused by hydrogen reduction in sodium ion exchange, making the hydrogen retention and sodium bicarbonate can not be re-absorbed from the urinary loss of;
③ renal tubular cells reduced ability to produce ammonia, the dysfunction of uric acid, alkali salts can not be retained. Generally no clinical symptoms of mild metabolic acidosis, severe acidosis, blood PH decreased anion gap was significantly higher than normal, patients with fatigue, anorexia, nausea, vomiting, abdominal pain, headache, irritability, deep and long breathing. In severe cases, coma, heart failure, blood pressure and cardiac arrest.
Two. Acidosis: acidosis is a common symptom in chronic renal failure.
When serum creatinine clearance rate dropped to 1/5 of the normal, it can not maintain a normal balance. The clinical manifestations of fatigue, nausea, vomiting, irritability, lethargy, chest tightness, deep breathing, and finally died of respiratory paralysis and shock.
3 Digestive System
Increase urea excluded from the intestinal system, intestinal bacterial decomposition of urease to ammonia, causing the disorder of digestive function.
Prominent symptoms of this disease-oriented to the earliest and most common, exacerbated with disease progression. Gastrointestinal symptoms, increased urea, broken down into ammonia and ammonium carbonate to stimulate gastrointestinal mucosa caused by bacteria, but also with increased gastrointestinal peptide hormone levels and metabolic disorders

Infiltration therapy of micro-based medicine how to block the treatment of renal failure.

Referred to "uremic" these three words, many kidney patients, especially patients with renal insufficiency will fear and fear. Renal insufficiency, kidney has been a moderate injury, treatment of poor developed into uremia is inevitable, a long-term dialysis or kidney transplantation to maintain was already fragile lives.
Kidney disease is a chronic disease, uremia, renal insufficiency, end-stage, began to suffer from kidney disease to renal insufficiency and then uremia, general slow take decades, fast will a few months.
But in this process, we can not help but ask a question, can delay or block the renal insufficiency developed into uremia? Does it have to face do not expect the fate of dialysis and renal transplantation? There is no third alternative road?
First, in order to better explain the problems we graphic way to illustrate, consider the following diagram.
Renal insufficiency (also called renal failure) a common clinical syndrome. Occurs in chronic renal disease, slowly decreased renal function to failure.
Under normal circumstances, according to the degree of impairment of renal function, renal dysfunction is divided into four: renal dysfunction in decompensated renal insufficiency in decompensated renal insufficiency, renal failure of renal insufficiency, uremia.
These four stages the condition gradually worsened, the symptoms gradually process.
Round stone boulders Law: on a hilltop by the Earth's gravitational pull, roll down from the top, which, if blocked, would have been rolled to the foot of the mountain. Rolling faster and faster, more and more difficult to stop. Renal function is like sinking boulders below the triangle as a mountain of renal insufficiency (renal failure) does not provide treatment and curb bound to be rolled down to the decompensation of renal insufficiency, renal insufficiency, decompensated of renal insufficiency, renal failure of will eventually be developed into uremia.
The four stages of renal insufficiency, the phenomenon of the point of view of renal function gradually deteriorated, the process of injury. Even in the normal renal function of patients, as long as his kidneys substantive disease, kidney damage, the possibility of disease, there continues to deteriorate, so his situation is like the top of the piece of boulders at the possibility of falling down , until the fall to the foot of the mountain to renal failure and uremia.
Patients with renal damage at this time standing at the crossroads of life:
First, to give up treatment
The second is to adopt a positive attitude with the treatment.
In the first case, to give up treatment
This condition is equivalent to that on the boulders without any hindrances, let it at their own pace. Boulders in the rolling process, the speed is gradually accelerated, and the more the faster rolling below.
Means that the patients of renal injury if not treated, the condition will rapidly deteriorate, yet decompensated renal insufficiency, decompensated to the renal failure stage. At this stage of development, if it did not take effective measures to remedy, it will be the rapid development of uremia.
So the condition just developed to renal injury, to give up treatment is to give up his life, renal insufficiency eventually developed into uremia.
Another reason a lot of renal insufficiency patients do not understand do not know, much less emphasis on trends and dangers of chronic renal insufficiency, no treatment or no treatment, but also mean giving up
The second case, adopt a positive attitude with the treatment.
Order to prevent the downward slide of boulders, you can set up obstacles to it, at least delay its rolling speed.
Treatment measures will be of two kinds:
There are questions to expert advice (Click to specialists Message);

Renal failure, creatinine 400 how do?

Renal failure, creatinine 400 how do? Renal failure patients fear most is watching a step by step of the creatinine increased, a check will be down from check value is not the same. But no way in the face of escalating creatinine values, renal failure, creatinine 400 What does this mean we should be how to treat. Let's find out more: so, I would like to ask the experts, please click consulting
Creatinine 400 means that the patients to renal insufficiency, renal failure, period, in accordance with the different values ​​of creatinine, kidney damage is divided into four:
(1) decompensated serum creatinine 141.4 ~ 177.O the micrograms molecules / L (1.6 to 2.0mg/dl), 20% ~ 25% reduction in nephron compensatory renal excretion and regulation functions were good, if there is proteinuria, patients with early morning may have mild eyelid edema, but generally no obvious symptoms.
(2) decompensated (azotemia) serum creatinine 185.9 ~ 442.6mmol / (2.1 ~ 5.0mg/dl), renal units from 50% to 70% reduction in renal excretion and regulation of the dysfunction, night urine, fatigue, edema, loss of appetite, nausea and mild anemia, occasional acidosis.
(3) the decompensated late (ie, uremia pre) serum creatinine> 442.6 to 708.2 micrograms molecules / L (5.0 ~ 8.0mg/dl), renal units, a decrease of 70% to 90%, patients often have severe anemia, edema, can be nausea, vomiting, metabolic acidosis, hypocalcemia and hyperphosphatemia. [I do not know, you want to ask an expert]
(4) the uremic of serum creatinine> 708.2 micrograms molecules / l (8.0mg/dl), symptoms of systemic poisoning is serious, more than a lot of water retention in the body.
Creatinine 400 patients has come to late renal injury, patients with kidney damage to more than 70% of early kidney damage is not treated, resulting in further exacerbated the injury with inflammation, cells of healthy kidney function phenotypic change, the release of a series of induced renal toxicity cells and the growth of chemokines, which synthesize and secrete a large number of difficult to be degradation of extracellular matrix. Due to the imbalance of synthesis and degradation of the dynamic balance mechanism, as well as a large number of extracellular matrix deposition and aggregation to replace a healthy functional units, there has been glomerulosclerosis; tubular degeneration and atrophy; interstitial tissue, vascular fibrosis. So a lot of creatinine did not break out, and high creatinine.
The face of renal failure, creatinine 400 many patients unable to do anything at this time can only dialysis treatment? Renal failure site, Dr. Wang answered: to treat lower creatinine must start from the root cause of creatinine - renal fibrosis in the treatment of a high serum creatinine, the traditional treatment is only a drop of serum creatinine, rather than to repair the basement membrane , so that serum creatinine does not decline, even if the decline, that is temporary. Micro therapy for the penetration of traditional Chinese medicine can clear the immune complexes lead to damage of the glomerular basement membrane and diseased tissue, repair of the glomerular basement membrane. As long as the damage to the basement membrane repair, change the structure of the kidney, the expansion of the glomerular filtration area, serum creatinine will gradually decline, but this requires a process to prevent a cold, diet and emotional, not tired control blood pressure, blood sugar, and other factors, to protect the kidney function. Just noticed these, serum creatinine must come down. High serum creatinine can not be blind to see the level of serum creatinine values ​​but should resolve this situation serum creatinine increased serum creatinine source, the glomerular basement membrane damage point of view, the only way to achieve the purpose of treatment serum creatinine .