samedi 28 juillet 2012

Renal failure, creatinine 400 how do?


Renal failure, creatinine 400 how do? Renal failure patients fear most is watching a step by step of the creatinine increased, a check will be down from check value is not the same. But no way in the face of escalating creatinine values, renal failure, creatinine 400 What does this mean we should be how to treat. Let's find out more: so, I would like to ask the experts, please click consulting
Creatinine 400 means that the patients to renal insufficiency, renal failure, period, in accordance with the different values ​​of creatinine, kidney damage is divided into four:
(1) decompensated serum creatinine 141.4 ~ 177.O the micrograms molecules / L (1.6 to 2.0mg/dl), 20% ~ 25% reduction in nephron compensatory renal excretion and regulation functions were good, if there is proteinuria, patients with early morning may have mild eyelid edema, but generally no obvious symptoms.
(2) decompensated (azotemia) serum creatinine 185.9 ~ 442.6mmol / (2.1 ~ 5.0mg/dl), renal units from 50% to 70% reduction in renal excretion and regulation of the dysfunction, night urine, fatigue, edema, loss of appetite, nausea and mild anemia, occasional acidosis.
(3) the decompensated late (ie, uremia pre) serum creatinine> 442.6 to 708.2 micrograms molecules / L (5.0 ~ 8.0mg/dl), renal units, a decrease of 70% to 90%, patients often have severe anemia, edema, can be nausea, vomiting, metabolic acidosis, hypocalcemia and hyperphosphatemia. [I do not know, you want to ask an expert]
(4) the uremic of serum creatinine> 708.2 micrograms molecules / l (8.0mg/dl), symptoms of systemic poisoning is serious, more than a lot of water retention in the body.
Creatinine 400 patients has come to late renal injury, patients with kidney damage to more than 70% of early kidney damage is not treated, resulting in further exacerbated the injury with inflammation, cells of healthy kidney function phenotypic change, the release of a series of induced renal toxicity cells and the growth of chemokines, which synthesize and secrete a large number of difficult to be degradation of extracellular matrix. Due to the imbalance of synthesis and degradation of the dynamic balance mechanism, as well as a large number of extracellular matrix deposition and aggregation to replace a healthy functional units, there has been glomerulosclerosis; tubular degeneration and atrophy; interstitial tissue, vascular fibrosis. So a lot of creatinine did not break out, and high creatinine.
The face of renal failure, creatinine 400 many patients unable to do anything at this time can only dialysis treatment? Renal failure site, Dr. Wang answered: to treat lower creatinine must start from the root cause of creatinine - renal fibrosis in the treatment of a high serum creatinine, the traditional treatment is only a drop of serum creatinine, rather than to repair the basement membrane , so that serum creatinine does not decline, even if the decline, that is temporary. Micro therapy for the penetration of traditional Chinese medicine can clear the immune complexes lead to damage of the glomerular basement membrane and diseased tissue, repair of the glomerular basement membrane. As long as the damage to the basement membrane repair, change the structure of the kidney, the expansion of the glomerular filtration area, serum creatinine will gradually decline, but this requires a process to prevent a cold, diet and emotional, not tired control blood pressure, blood sugar, and other factors, to protect the kidney function. Just noticed these, serum creatinine must come down. High serum creatinine can not be blind to see the level of serum creatinine values ​​but should resolve this situation serum creatinine increased serum creatinine source, the glomerular basement membrane damage point of view, the only way to achieve the purpose of treatment serum creatinine .

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