1, treatment of renal failure for the cause
of treatment
For the treatment of the cause of renal
failure treatment from the "source". The cause of renal failure
because of a variety of causes kidney therefore inherent cell deformation and
damage. With glomerular renal failure, for example, can explain our method of
treatment: glomerular disease is an autoimmune disease, predisposing factors
often combine to form immune complexes by the antigen or antibody, and
deposition in glomeruli (immune complexes). The participation of inflammatory
mediators (such as complement, interleukins, reactive oxygen species, etc.),
and finally lead to glomerular injury. In the practice of treatment, the
following measures:
(1) expansion of the renal artery,
increasing the effective perfusion of the renal glomerular, tubular, quality,
and accelerated damage to the cell i dependent, alleviate hypoxia.
(2) expansion of the systemic arterial
blood, reduce and mitigate the high pressure of the body, especially to reduce
glomerular pressure, reduce glomerular consider high state.
(3) formed by speeding up the method of
dependents to avoid endothelial cells are not activated to inhibit the
micro-tied.
(4) has been activated inflammatory cells
to speed up the blood speed and in sufficient quantities to support, to inhibit
chemotaxis and infiltration of a series of inflammatory factors, prevent
abnormal release.
Clinical observation of reality, through
the implementation of more than four treatment measures, the normal metabolic
function of the glomerulus is activated, the when glomerular situation
improved, the whole kidney function also will improve
2, treatment of renal failure was followed
for the treatment of the disease process
The process of development of chronic renal
failure, effective renal units gradually decreased renal function loss. In this
process, the kidneys gradually shrink, and a large number of
glomerulosclerosis, tubulo - interstitial fibrosis. Therefore, the process of
renal failure, deepening the process is the extent of renal fibrosis. Blocking
renal fibrosis process for effective control of disease progression to uremia
is important.
Blocking the process of renal fibrosis has
been a major problem in the medical profession, although there are some
research institutions that some traditional Chinese medicine has a certain
effect of blocking the process of renal fibrosis, but the real applications are
not many clinical. Hospital use of the drug is processed by the micro-based
series of traditional Chinese medicine. Chinese medicine treatment by
micro-technology, the increased activity of many medicines, it is difficult to
play a role in the traditional conditions can also be brought into full play
the role.
Renal fibrosis and the formation of a large
number of extracellular matrix synthesis and accumulation has played a key
role. The excessive accumulation of extracellular matrix will lead to organizational
results and loss of function of the kidneys. In this process, the
myofibroblasts to generate its major role in the synthesis of extracellular
matrix can also be said that the myofibroblast is the main source of
extracellular matrix. To this end blocking renal fibrosis process, must be
blocked into the renal interstitial fibroblasts to myofibroblasts, transformed
into a fundamental part. Hospital breakthrough synthesis of difficult to
degrade collagen, and its mechanism: Effects of active substances in the human
body and myofibroblasts molecules close integration (molecular valence bond),
after fusion, the composition of myofibroblasts degradation, prompting muscle
fibroblast cell lysis, and fragmentation. Cracking, broken myofibroblasts
phagocytes or pieces excreted.
The key to the core of treatment for renal
failure in the disease process is blocked by the deterioration of renal
fibrosis chain blocking renal fibrosis and deterioration of the chain is found
to prevent normal cells into myofibroblasts of drugs.
3, treatment of renal failure was followed
by treatment for symptoms
Clinical symptoms of chronic renal failure
patients, most of the water and electrolyte and acid-base balance; otherwise
renal failure symptoms and uremia toxin. For the treatment of symptoms can
improve the internal environment disorder regulating kidney imbalance, improve
the quality of life of patients with renal failure.
Micro therapy for the penetration of
traditional Chinese medicine in the treatment of renal failure in the process,
the specific way:
(1) one of the common symptoms of renal
failure - renal anemia treatment
Herbal active substance recombinant human
erythropoietin (EPO) (Rhepo, hereinafter referred to as EPO) treatment of renal
anemia. Clinical observations indicate that the effect is very significant.
This therapy is generally applicable to patients with anemia. In general,
patients with renal failure, especially in maintenance hemodialysis patients,
long-term small amount of blood loss will cause the loss of some blood raw,
such as iron and folic acid. In order to enable the EPO to fully play its role
to make up some blood raw to use the EPO. Chinese medicine active substance is
rich in 10 kinds of trace elements, including iron and folic acid, and fully meet
to improve the needs of the anemic condition.
(2) for the treatment of renal failure,
high blood pressure
Hypertension is a reversible disease, for
which we paid great attention to seize this part of the process of treatment of
chronic renal failure. Long-term tightening of state of the renal blood vessels
is the cause of renal hypertension, treatment of hypertension is the most
important and effective means to directly dilate blood vessels. We found in the
clinical course, processed by the micro-based medicine in a large number of
vascular relaxing factor synergies, so that the blood vessels to become a
degree of relaxation, and therefore alleviate the renal hypertensive blood
vessels caused by excessive diastolic inadequate, nervous, powerful alleviate the
symptoms of renal failure patients.
(3) the treatment of metabolic acidosis,
renal failure, clinical symptoms -
Although acidosis is a very common clinical
symptoms of renal failure disease, but according to our clinical: moderate
degree of acidosis, there is no very serious implications for patients with
renal failure. But when the carbon dioxide combining power is lower than 13mmol
/ L (30 volume%), especially associated with coma or deep breathing, a severe
acidosis, in this case, the veins fill rapidly to correct acid alkaline
poisoning. However, for patients with heart failure, if too much emphasis may
be possible to correct the acidosis and a large number of vein fill alkali, a
certain degree of risk, it should be under conditions of strict low sodium
diet, patients with a small amount of times bicarbonate sodium. Renal failure
patients with hyponatremia and low edema, should not the sodium, should be
given to The THAM. In addition, patients given enough heat, the injection of
protein synthesis agent Nandrolone phenylpropionate emphasis on avoiding the
use of diuretics producing acids and cation exchange resin. Should be noted
that we are dealing with acidosis is not the purpose of acidosis, but chronic
renal insufficiency patients as a whole. Treatment to correct the acidosis,
under normal circumstances do not need to carbon dioxide combining power
increased to normal, a corrective to 17mmol / L (38 volume%) will be able to.
4, treatment for renal failure patients
with renal function recovery
For the etiology, pathogenesis, symptoms,
treatment, mitigation and control of the disease, but for patients with renal
failure, just is not enough to control the disease. Fibrosis or sclerosis,
kidney or solitary kidney atrophy, especially in the uremic period, only about
10% of the residual renal units, if not yet thousands of necrosis of the kidney
nephron because of renal failure patients in a large number of compromised unit
to repair the renal units were still remnants of the "overload" when
a long course of time, inevitably there will be lesions. This is why many
patients permanently, the condition is repeated. In order to solve this problem
from a fundamental and effective way is to impaired renal unit repair, it
restored the metabolic capacity.
Impaired kidney repair is a complex systems
engineering, is currently at home and abroad attaches great importance to the
research topic and focus. Kidney repair is difficult, slow, no significant
effect of restricting the development of medical science. Shijiazhuang kidney disease hospital in the
treatment of kidney disease in clinical practice, the Group found that the
active substances produced by the reasonable use of Chinese medicine has a
unique effect in the kidney repair.
(1) to improve the internal environment
disorder patients, promote protein synthesis, added repair material nutrition
lay the material foundation for kidney repair.
(2) by regulating the mesangial cells,
glomerular capillary endothelial cells and epithelial cells to repair the
structure of the glomerular basement membrane, to restore its selective
filtering, expand filtration area, to speed up the excretion of toxins .
(3) by promoting the synthesis of heparan
sulfate and sialic acid protein to maintain the charge barrier function,
inhibiting its decomposition. Strengthen the charge barrier function, decreased
protein leakage.
(4) by inhibiting the synthesis of
low-density protein LDL, OX-LDL, reduce damage on the charge barrier to
continue to repair the glomerular charge barrier function, to reduce and
prevent leakage due to a large number of protein and tubular high metabolic and
renal ball sclerosis, tubular, and renal interstitial fibrosis.
In the actual process of renal failure
treatment, because we use traditional Chinese medicine active substances rich
in a variety of vitamins organic acids promote kidney repair, can fully meet
the supplementary material required for kidney repair, and then by adjusting to
improve the immune system, improve within the environment to achieve the
purpose of repair of the kidney.
In renal failure treatment, should not only
unity of treatment for certain symptoms or laboratory indicators. Infiltration
therapy of micro-based traditional Chinese medicine for its processing of
traditional Chinese medicine, can have the ability to more full efficacy in the
specific treatment of renal failure in the process of very obvious quick,
efficient, permanent cure. Another departure from the process point of view of
blocking renal fibrosis is the real root of the problem in the treatment of
chronic renal failure.
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